PLGA (75:25)
PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA) . PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides[1][2][3].
Product Specifications
CAS Number
34346-01-5
Product Name Alternative
Poly (lactic-co-glycolic acid) (75:25)
UNSPSC
12352211
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/plga-75-25.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)C(C)OC(CO[H])=O.[x].[y]
References & Citations
[1]Mura S, et al. Influence of surface charge on the potential toxicity of PLGA nanoparticles towards Calu-3 cells. Int J Nanomedicine. 2011;6:2591-605. |[2]D'Souza S, et al. Development of Risperidone PLGA Microspheres. J Drug Deliv. 2014;2014:620464. |[3]Makadia HK, et al. Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier. Polymers (Basel) . 2011 Sep 1;3 (3) :1377-1397. |[4]Chung TW, Tsai YL, Hsieh JH, Tsai WJ. Different ratios of lactide and glycolide in PLGA affect the surface property and protein delivery characteristics of the PLGA microspheres with hydrophobic additives. J Microencapsul. 2006;23 (1) :15-27.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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