Lactoferrin (17-41)

Lactoferrin 17-41 (Lactoferricin B), a peptide corresponding to residues 17-41 of bovine lactoferrin, has antimicrobial activity against a wide range of microorganisms, including Gram-positive and Gramnegative bacteria, viruses, protozoa, and fungi. Lactoferrin 17-41 has antitumor activities[1][2].

Product Specifications

CAS Number

[146897-68-9]

Product Name Alternative

Lactoferricin B; Lfcin B

UNSPSC

12352209

Target

Apoptosis; Bacterial; Fungal

Type

Peptides

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/lactoferrin-17-41.html

Purity

98.89

Solubility

10 mM in DMSO

Smiles

O=C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1[C@](CCC1)([H])C(N[C@H](C(N[C@@](C(N[C@@](C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N[C@H](C(N2)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)NC([C@H](CCCCN)NC([C@@H](N)CC3=CC=CC=C3)=O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)([H])[C@H](O)C)=O)([H])[C@@H](C)CC)=O)CO)=O)=O)C)=O)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)CCSC)=O)CCCNC(N)=N)=O)CC5=CNC6=CC=CC=C56)=O)CCC(N)=O)[C@@H]2CC7=CNC8=CC=CC=C78

Molecular Formula

C141H224N46O29S3

Molecular Weight

3123.77

References & Citations

[1]Samuelsen Ø, et al. Anti-complement effects of lactoferrin-derived peptides. FEMS Immunol Med Microbiol. 2004 Jun 1;41 (2) :141-8.|[2]Jiang R, et al. Bovine lactoferrin and lactoferricin exert antitumor activities on human colorectal cancer cells (HT-29) by activating various signaling pathways. Biochem Cell Biol. 2017 Feb;95 (1) :99-109.|[3]Latorre D, et al. Reciprocal interactions between lactoferrin and bacterial endotoxins and their role in the regulation of the immune response. Toxins (Basel) . 2010;2 (1) :54‐68.