DFHBI-1T

DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm) . DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells[1][2].

Product Specifications

CAS Number

[1539318-36-9]

UNSPSC

12171500

Hazard Statement

H302-H312-H332

Target

DNA Stain

Type

Dye Reagents

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dfhbi-1t.html

Purity

98.11

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1N(CC(F)(F)F)C(C)=N/C1=C\C2=CC(F)=C(O)C(F)=C2

Molecular Formula

C13H9F5N2O2

Molecular Weight

320.21

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Wenjiao Song, et al. Plug-and-play fluorophores extend the spectral properties of Spinach. J Am Chem Soc. 2014 Jan 29;136 (4) :1198-201.|[2]Grigory S Filonov, et al. Broccoli: rapid selection of an RNA mimic of green fluorescent protein by fluorescence-based selection and directed evolution. J Am Chem Soc. 2014 Nov 19;136 (46) :16299-308.