Nicousamide
Nicousamide is a potent inhibitor of TGF-β RII phosphorylation. Nicousamide can be used to study renal fibrosis in animal models of diabetic nephropathy[1].
Product Specifications
CAS Number
704881-43-6
UNSPSC
12352005
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/nicousamide.html
Smiles
O=C(C1=CC(NC(C2=CC3=CC([N+]([O-])=O)=C(C(C)=C3OC2=O)O)=O)=CC=C1O)O
Molecular Formula
C18H12N2O9
Molecular Weight
400.30
References & Citations
[1]Zhang H, et al. Nicousamide, a potent inhibitor of phosphorylation by TGF-β receptor II. Acta Pharmaceutica Sinica B, 2011, 1 (3) : 160-165.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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