Cinnamyl Alcohol-d5
Cinnamyl Alcohol-d5 is deuterated labeled Cinnamyl Alcohole. Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, exhibits anti-obesity, antioxidant and anti-inflammatory activities[1].
Product Specifications
CAS Number
1044940-87-5
UNSPSC
12352005
Target
Akt; AMPK; ERK; Isotope-Labeled Compounds; NO Synthase; Potassium Channel; PPAR; ROCK
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Epigenetics; Immunology/Inflammation; MAPK/ERK Pathway; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR; Stem Cell/Wnt; TGF-beta/Smad; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
OC/C=C/C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H]
Molecular Formula
C9H5D5O
Molecular Weight
139.21
References & Citations
[2]Choi YR, et al., Cinnamyl Alcohol Attenuates Adipogenesis in 3T3-L1 Cells by Arresting the Cell Cycle. Int J Mol Sci. 2024 Jan 5;25 (2) :693.|[3]Kang YH, et al., Cinnamyl alcohol attenuates vasoconstriction by activation of K⁺ channels via NO-cGMP-protein kinase G pathway and inhibition of Rho-kinase. Exp Mol Med. 2012 Dec 31;44 (12) :749-55.|[4]Lee H S. Chemical composition of Cinnamomum cassia leaf oils and suppression effect of cinnamyl alcohol on nitric oxide synthase[J]. Journal of the Korean Society for Applied Biological Chemistry, 2009, 52: 480-485.|[5]Zou L, et al., The anti-inflammatory effects of cinnamyl alcohol on sepsis-induced mice via the NLRP3 inflammasome pathway. Ann Transl Med. 2022 Jan;10 (2) :48.|[1]Hwang DI, et al. Cinnamyl Alcohol, the Bioactive Component of Chestnut Flower Absolute, Inhibits Adipocyte Differentiation in 3T3-L1 Cells by Downregulating Adipogenic Transcription Factors. Am J Chin Med. 2017;45 (4) :833-846.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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