CCT365623 (hydrochloride)
CCT365623 hydrochloride is an orally active lysyl oxidase (LOX) inhibitor, with an IC50 of 0.89 μM. CCT365623 hydrochloride suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF. CCT365623 hydrochloride is extremely well tolerated, and has good pharmacokinetic properties[1].
Product Specifications
CAS Number
2126136-98-7
UNSPSC
12352005
Target
Akt; EGFR; Monoamine Oxidase; TGF-beta/Smad
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Neuronal Signaling; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cct365623-hydrochloride.html
Purity
98.07
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
NCC1=CC=C(S(=O)(C2=CC(C3=CC=CC=C3)=CC(S(=O)(C)=O)=C2)=O)S1.Cl
Molecular Formula
C18H18ClNO4S3
Molecular Weight
443.99
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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