Mitochondrial respiration-IN-4
Product Specifications
UNSPSC Description
Mitochondrial respiration-IN-4 (Compound TC11) is a potent mitochondrial respiration inhibitor. Mitochondrial respiration-IN-4 impairs Reactive Oxygen Species (ROS) in and induces apoptosis in MCF7 cells[1].
Target Antigen
Mitochondrial Metabolism; Reactive Oxygen Species
Type
Reference compound
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mitochondrial-respiration-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C)NC(/C=C2C(NC3=C\2C=CC(C4=CC=C(NS(=O)(C5=CC=C(F)C(Cl)=C5)=O)C=C4)=C3)=O)=C1C)NCCN(CC)CC
Molecular Weight
664.19
References & Citations
[1]Helmy SWA, et al. Novel sulfonamide-indolinone hybrids targeting mitochondrial respiration of breast cancer cells. Eur J Med Chem. 2024 Feb 17;268:116255.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161267/Mitochondrial-respiration-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161267/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6177665-01 0.1 mL
HAVCR1 (Hepatitis A Virus Cellular Receptor 1, HAVCR, HAVCR-1, KIM-1, KIM1, TIM-1, TIM1, TIMD1) (FITC)
Ask
View Details MBS6177665-02 5x 0.1 mL
HAVCR1 (Hepatitis A Virus Cellular Receptor 1, HAVCR, HAVCR-1, KIM-1, KIM1, TIM-1, TIM1, TIMD1) (FITC)
Ask
View Details