2-Iminobiotin (hydrobromide)
2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5 μM for murine iNOS and rat n-cNOS, respectively[1]. 2-Iminobiotin hydrobromide superimposes on hypothermia protects human neuronal cells from hypoxia-induced cell damage[2].
Product Specifications
CAS Number
76985-52-9
Product Name Alternative
Guanidinobiotin (hydrobromide)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/2-iminobiotin-hydrobromide.html
Purity
98.27
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
[H][C@](CS[C@H]1CCCCC(O)=O)([C@]1([H])N2)NC2=N.Br
Molecular Formula
C10H18BrN3O2S
Molecular Weight
324.24
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
INOS
Available Sizes
Frequently Asked Questions
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