SU 3327
SU 3327 is a selective inhibitor of c-Jun N-terminal kinase (JNK). It shows an IC₅₀ of 0.7 μM in the kinase assay. It Inhibits the protein-protein interaction between JNK and JIP with an IC₅₀ of 239 nM. It inhibits TNF-α stimulated phosphorylation of c-Jun in cells with an EC₅₀ of 6.23 μM. It restores insulin sensitivity in a mouse model of type-2 diabetes.
Product Specifications
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months
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MBS6160146-01 0.1 mL
SCN3A (Sodium Channel Protein Type 3 Subunit alpha, Sodium Channel Protein Brain III Subunit alpha, Sodium Channel Protein Type III Subunit alpha, Voltage-gated Sodium Channel Subtype III, Voltage-gated Sodium Channel Subunit alpha Nav1.3, KIAA1356, NAC3)
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