IA2, Human (293a.a, N-His)

The IA2 protein is critical in the vesicle-mediated secretion process and is essential for the accumulation of secretory vesicles in the hippocampus, pituitary gland, and pancreatic islets. IA2 is critical for insulin-related functions, ensuring normal levels of insulin-containing vesicles, preventing degradation and promoting glucose-stimulated insulin secretion. IA2 Protein, Human (293a.a, N-His) is the recombinant human-derived IA2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IA2 Protein, Human (293a.a, N-His) is 293 a.a., with molecular weight of ~35 kDa.

MDISTGHMIL AYMEDHLRNR DRLAKEWQAL CAYQAEPNTC ATAQGEGNIK KNRHPDFLPY DHARIKLKVE SSPSRSDYIN ASPIIEHDPR MPAYIATQGP LSHTIADFWQ MVWESGCTVI VMLTPLVEDG VKQCDRYWPD EGASLYHVYE VNLVSEHIWC EDFLVRSFYL KNVQTQETRT LTQFHFLSWP AEGTPASTRP LLDFRRKVNK CYRGRSCPII VHCSDGAGRT GTYILIDMVL NRMAKGVKEI DIAATLEHVR DQRPGLVRSK DQFEFALTAV AEEVNAILKA LPQ