(-) -GSK598809 (hydrochloride)
(-) -GSK598809 is an isomer of GSK598809. GSK598809 is a potent and selective dopamine D3 Receptor (DRD3) antagonist.
Product Specifications
CAS Number
[863766-31-8]
Product Name Alternative
(1S,5R) -GSK598809 (hydrochloride)
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/minus-gsk598809-hydrochloride.html
Concentration
10mM
Purity
99.64
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC1=C(C2=NN=C(SCCCN3C[C@@]4(C5=CC=C(C(F)(F)F)C=C5F)C[C@@]4([H])C3)N2C)OC=N1.[H]Cl
Molecular Formula
C22H24ClF4N5OS
Molecular Weight
517.97
References & Citations
[1]Appel NM, et al. Dopamine D3 Receptor Antagonist (GSK598809) Potentiates the Hypertensive Effects of Cocaine in Conscious, Freely-Moving Dogs. J Pharmacol Exp Ther. 2015 Sep;354 (3) :484-92.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D3 Receptor
Available Sizes
Curated Selection
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