Cucurbitacin B
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity[1][2][3][4][5].
Product Specifications
CAS Number
6199-67-3
UNSPSC
12352211
Hazard Statement
H300
Target
Apoptosis; Autophagy; COX; Endogenous Metabolite; HIF/HIF Prolyl-Hydroxylase; Integrin; ROS Kinase
Type
Natural Products
Related Pathways
Apoptosis; Autophagy; Cytoskeleton; Immunology/Inflammation; Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease; Others
Assay Protocol
https://www.medchemexpress.com/Cucurbitacin-B.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
O[C@H](C1)[C@@]([C@@](C)(O)C(/C=C/C(OC(C)=O)(C)C)=O)([H])[C@](C2)(C)[C@]1(C)[C@]3([H])CC=C4C(C)(C)C([C@@H](O)C[C@@]4([H])[C@]3(C)C2=O)=O
Molecular Formula
C32H46O8
Molecular Weight
558.70
Precautions
H300
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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