Centanafadine
Centanafadine is dual norepinephrine (NE) /dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC50s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively.
Product Specifications
CAS Number
[924012-43-1]
Product Name Alternative
EB-1020
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Adrenergic Receptor; Dopamine Transporter; Serotonin Transporter
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Centanafadine.html
Purity
99.62
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
[C@@H]12[C@@](CNC2)(C3=CC(C=CC=C4)=C4C=C3)C1
Molecular Formula
C15H15N
Molecular Weight
209.29
Precautions
H315, H319, H320
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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