Androgen receptor allosteric antagonist 1
Androgen receptor allosteric antagonist 1 (compound D36) is a a llosteric, competitive androgen receptor (AR) antagonist with the Ki of 9 μM. Androgen receptor allosteric antagonist 1 inhibits R1881-mediated transcription and proliferation and can be used for study of prostate cancer[1].
Product Specifications
CAS Number
927819-39-4
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/androgen-receptor-allosteric-antagonist-1.html
Smiles
O=C(CC1=CN(CC(C)C)C2=CC=C(C3=C(OC)C=CC=C3)C=C21)N
Molecular Formula
C21H24N2O2
Molecular Weight
336.43
References & Citations
[1]Joseph JD, et al. Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists. Proc Natl Acad Sci U S A. 2009;106 (29) :12178-12183.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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