PAK6, Human (His)
PAK6, a dynamic serine/threonine kinase, regulates gene transcription activated by AR or MAP2K6/MAPKK6. It phosphorylates and inhibits AR-mediated transcription, hindering ESR1-mediated transcription. PAK6 interacts with IQGAP1, suggesting a role in cytoskeleton regulation. Moreover, it protects cells from apoptosis by phosphorylating BAD, showcasing its multifaceted impact on transcriptional control and cytoskeletal dynamics. PAK6 Protein, Human (His) is the recombinant human-derived PAK6 protein, expressed by E. coli , with N-6*His labeled tag.
Product Specifications
Product Name Alternative
PAK6 Protein, Human (His), Human, E. coli
UNSPSC
12352202
Type
Reference compound
Assay Protocol
https://www.medchemexpress.com/cytokines/pak6-protein-human-his.html
Molecular Formula
106821730 (Gene_ID) Q9NQU5 (G383-Y674) (Accession)
Shipping Conditions
Dry ice.
Scientific Category
Recombinant Proteins
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