CYC-116

693228-63-6

12352005

H315, H319, H320

Aurora Kinase

Reference compound

Cell Cycle/DNA Damage; Epigenetics

Cancer-Kinase/protease

Cancer

https://www.medchemexpress.com/CYC-116.html

99.05

DMSO : 15 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 80°C)

CC1=C(SC(N)=N1)C2=NC(NC3=CC=C(C=C3)N4CCOCC4)=NC=C2

C18H20N6OS

368.46

H315, H319, H320

[1]Wang S, et al. Discovery of N-phenyl-4- (thiazol-5-yl) pyrimidin-2-amine aurora kinase inhibitors. J Med Chem. 2010 Jun 10;53 (11) :4367-78.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

Reference compound1

Phase 1

Aurora A; Aurora B