IND24
IND24 is a potent antiprion agent with an EC50 value of 1.27 µM. IND24 decreases abnormal, misfolded, pathogenic forms of benign normally occurring prion protein on the cell surface or inside the cell[1].
Product Specifications
CAS Number
1426047-44-0
UNSPSC
12352005
Target
Prion Protein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ind24.html
Purity
99.57
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC1=CC=CC(NC2=NC(C3=CC=C(C=C3)C4=CC=CC=C4)=CS2)=N1
Molecular Formula
C21H17N3S
Molecular Weight
343.44
References & Citations
[1]Silber BM, et al. Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice. Pharm Res. 2013 Apr;30 (4) :932-50.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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