2'-Deoxyuridine-2′-13C

2'-Deoxyuridine-2′-13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]</

Product Specifications

CAS Number

[478510-87-1]

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/2-deoxyuridine-2-13c.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C=CC(N1)=O)[C@]2([H])O[C@@H]([C@H]([13CH2]2)O)CO

Molecular Formula

C8 13CH12N2O5

Molecular Weight

229.19

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Reidy JA, et al. Deoxyuridine increases folate-sensitive fragile site expression in human lymphocytes. Am J Med Genet. 1987 Jan;26 (1) :1-5.