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2'-Deoxyuridine-2′-13C

Product Specifications

UNSPSC Description

2'-Deoxyuridine-2′-13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]</

Target Antigen

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease;Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/2-deoxyuridine-2-13c.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C=CC(N1)=O)[C@]2([H])O[C@@H]([C@H]([13CH2]2)O)CO

Molecular Weight

229.19

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Reidy JA, et al. Deoxyuridine increases folate-sensitive fragile site expression in human lymphocytes. Am J Med Genet. 1987 Jan;26(1):1-5.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-D0186S1/2-Deoxyuridine-2-13C-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-D0186S1/

Clinical Information

No Development Reported

CAS Number

478510-87-1

Available Sizes

Curated Selection

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