TC-2153
TC-2153 is a selective inhibitor of striatal-enriched protein tyrosine phosphatase (STEP), with psychotropic activity and low acute toxicity. TC-2153 increases the expression of brain-derived neurotropic factor (BDNF) in the brain. And it decreases MAOA and 5-HT1A receptors mRNA level in midbrain. TC-2153 also inhibits 5-HT2A receptor-mediated signaling[1].
Product Specifications
CAS Number
[1381769-23-8]
UNSPSC
12352005
Target
5-HT Receptor; Monoamine Oxidase
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tc-2153.html
Concentration
10mM
Purity
98.73
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=C2SSSSSC2=CC(C(F)(F)F)=C1.[H]Cl
Molecular Formula
C7H5ClF3NS5
Molecular Weight
355.89
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor;5-HT2 Receptor; MAO-A; mLAG-3; α-1 microglobulin
Available Sizes
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