Anti-α-1-antichymotrypsin Antibody

Mouse Monoclonal Antibody specific to α-1-antichymotrypsin

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3 [Cleaved into: α-1-antichymotrypsin His-Pro-less]

Gene Name

SERPINA3

Gene ID

NCBI Gene ID

<a href="https://www.ncbi.nlm.nih.gov/gene/?term=SERPINA3">SERPINA3</a>

UniProt

P01011

Accession Number

NP_001076

Cellular Locus

Secreted.

Host

Mouse

Reactivity

Human

Immunogen

Purified human serum alpha-1-antichymotrypsin.

Target Antigen

α-1-antichymotrypsin

Target

α-1-antichymotrypsin

Clonality

Monoclonal

Isotype

IgG2a

Type

Antibody

Applications

ELISA

Field of Research

Enzymes

Purification Method

Purified by protein G affinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. {PubMed:2404007}.

Additionnal Information

These antibodies have been qualified for use in ELISA to detect human a1AC. <br><br>End users should determine optimal concentrations for their applications.