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C-Fms-IN-13

C-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor with an IC50 value of 17 nM. c-Fms-IN-13 can be used as an anti-inflammatory agent[1].

Product Specifications

CAS Number

885704-58-5

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

C-Fms

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/c-fms-in-13.html

Purity

99.27

Solubility

DMSO : 31.25 mg/mL (ultrasonic)

Smiles

N#CC1=CC=C(C(NC2=CC=C(N3CCCCC3)C=C2N4CCCCC4)=O)O1

Molecular Formula

C22H26N4O2

Molecular Weight

378.47

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Illig CR, et al. Discovery of novel FMS kinase inhibitors as anti-inflammatory agents. Bioorg Med Chem Lett. 2008 Mar 1;18 (5) :1642-8.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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