C-Fms-IN-13
C-Fms-IN-13 (compound 14) is a potent FMS kinase inhibitor with an IC50 value of 17 nM. c-Fms-IN-13 can be used as an anti-inflammatory agent[1].
Product Specifications
CAS Number
[885704-58-5]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
C-Fms
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/c-fms-in-13.html
Purity
99.27
Solubility
DMSO : 31.25 mg/mL (ultrasonic)
Smiles
N#CC1=CC=C(C(NC2=CC=C(N3CCCCC3)C=C2N4CCCCC4)=O)O1
Molecular Formula
C22H26N4O2
Molecular Weight
378.47
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Illig CR, et al. Discovery of novel FMS kinase inhibitors as anti-inflammatory agents. Bioorg Med Chem Lett. 2008 Mar 1;18 (5) :1642-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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