Human ATG4B Protein

<strong>Human ATG4B Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011805_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 500 µg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Cysteine protease ATG4B protein, Autophagin 1 protein, ATGB 4 protein, AUTL1 protein, Autophagin-1 protein, ATGB 4, ATGB-4, ATGB-4 protein, ATG4B_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Zhou B, Liu J, Kang R, Klionsky DJ, Kroemer G, Tang D. Ferroptosis is a type of autophagy-dependent cell death Semin Cancer Biol. 2020 Nov;66:89-100._x000D_ 2: Huang T, Kim CK, Alvarez AA, Pangeni RP, Wan X, Song X, Shi T, Yang Y, Sastry N, Horbinski CM, Lu S, Stupp R, Kessler JA, Nishikawa R, Nakano I, Sulman EP, Lu X, James CD, Yin XM, Hu B, Cheng SY. MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma Cancer Cell. 2017 Dec 11;32(6):840-855.e8._x000D_ 3: Ho CJ, Samarasekera G, Rothe K, Xu J, Yang KC, Leung E, Chan M, Jiang X, Gorski SM. Puncta intended: connecting the dots between autophagy and cell stress networks Autophagy. 2021 Apr;17(4):1028-1033._x000D_ 4: Huang R, Xu X, Liang Y, Zhang L, Wang T, Zhou L, DU N, Ye Q. [The expression, purification and characterization of human His-ATG4B protein] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2015 Feb;31(2):173-6._x000D_ 5: Agrotis A, Pengo N, Burden JJ, Ketteler R. Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells Autophagy. 2019 Jun;15(6):976-997._x000D_ 6: Han Z, Zhang W, Ning W, Wang C, Deng W, Li Z, Shang Z, Shen X, Liu X, Baba O, Morita T, Chen L, Xue Y, Jia D. Model-based analysis uncovers mutations altering autophagy selectivity in human cancer Nat Commun. 2021 May 31;12(1):3258._x000D_ 7: Durgan J, Lystad AH, Sloan K, Carlsson SR, Wilson MI, Marcassa E, Ulferts R, Webster J, Lopez-Clavijo AF, Wakelam MJ, Beale R, Simonsen A, Oxley D, Florey O. Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine Mol Cell. 2021 May 6;81(9):2031-2040.e8._x000D_ 8: Wu S, Su J, Qian H, Guo T. SLC27A4 regulate ATG4B activity and control reactions to chemotherapeutics-induced autophagy in human lung cancer cells Tumour Biol. 2016 May;37(5):6943-52._x000D_ 9: Nguyen TN, Padman BS, Zellner S, Khuu G, Uoselis L, Lam WK, Skulsuppaisarn M, Lindblom RSJ, Watts EM, Behrends C, Lazarou M. ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system Mol Cell. 2021 May 6;81(9):2013-2030.e9._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/33077263">10: Yang G, Li Y, Zhao Y, Ouyang L, Chen Y, Liu B, Liu J. Targeting Atg4B for cancer therapy: Chemical mediators Eur J Med Chem. 2021 Jan 1;209:112917. </a>_x000D_ _x000D_ <strong>Products Related to Human ATG4B Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>