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Anti-Mouse CD40 Antibody (FGK4.5/FGK45)

Anti-Mouse CD40 Antibody (FGK4.5/FGK45) is an agonistic rat-derived IgG2a monoclonal antibody targeting mouse CD40. Anti-Mouse CD40 Antibody (FGK4.5/FGK45) enhances T cells responses, dendritic cells maturation and NK cells activation. Anti-Mouse CD40 Antibody (FGK4.5/FGK45) can be used for the researches of cancer, infection, inflammation and immunology, such as CT26 tumor, vesicular stomatitis virus (VSV) infection and transplantation[1][2][3].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

TNF Receptor; Transmembrane Glycoprotein

Type

Inhibitory Antibodies

Related Pathways

Apoptosis; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-cd40-antibody-fgk4-5-fgk45.html

Purity

95.00

Smiles

[Anti-MouseCD40Antibody(FGK4.5/FGK45)]

Molecular Weight

(150 kDa)

References & Citations

[1]Zhang M, et al. Interleukin-15 combined with an anti-CD40 antibody provides enhanced therapeutic efficacy for murine models of colon cancer. Proc Natl Acad Sci U S A. 2009 May 5;106 (18) :7513-8.|[2]Zickovich JM, et al. Agonistic anti-CD40 enhances the CD8+ T cell response during vesicular stomatitis virus infection. PLoS One. 2014 Aug 28;9 (8) :e106060.|[3]Conde P, et al. DC-SIGN (+) Macrophages Control the Induction of Transplantation Tolerance. Immunity. 2015 Jun 16;42 (6) :1143-58.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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