FPL 62129
FPL 62129 is an antagonist for calcium channel. FPL 62129 reduces blood pressure and total peripheral resistance, increases the cardiac contractility and cardiac output in anarsthetised beagle model. FPL 62129 also serves as a vasodilator and a direct decelerator[1].
Product Specifications
CAS Number
95445-79-7
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/fpl-62129.html
Smiles
O=C(C1=C(CF)NC(C)=C(C(OC(C)C)=O)C1C2=C(F)C=CC(Cl)=C2C(F)(F)F)OC
Molecular Formula
C20H19ClF5NO4
Molecular Weight
467.81
References & Citations
[1]Humphries RG, et al., Cardiovascular profile of FPL 62129, a novel dihydropyridine calcium channel blocker, in anaesthetised dogs: a comparison with nifedipine. J Cardiovasc Pharmacol. 1988 Mar;11 (3) :332-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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