AChE-IN-27
AChE-IN-27 (compound 8c) is an AChE inhibitor (IC50=0.19 µM) . AChE-IN-27 can be used in studies of neurological diseases such as alzheimer's disease, dementia, ataxia and myasthenia gravis[1].
Product Specifications
CAS Number
177028-90-9
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-27.html
Purity
98.27
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N#CC(C1C2=CC=C(C)C=C2)=C(N)OC(C3=CC=CC=C3O4)=C1C4=O
Molecular Formula
C20H14N2O3
Molecular Weight
330.34
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Bouazizi Y, et al. Synthesis of new 3, 4-dihydropyrano [c] chromene derivatives and their evaluation as acetyl cholinesterase inhibitors[J]. European Journal of Chemistry, 2014, 5 (3) : 457-462.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE
Available Sizes
Frequently Asked Questions
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