AChE-IN-27

AChE-IN-27 (compound 8c) is an AChE inhibitor (IC50=0.19 µM) . AChE-IN-27 can be used in studies of neurological diseases such as alzheimer's disease, dementia, ataxia and myasthenia gravis[1].

Product Specifications

CAS Number

[177028-90-9]

UNSPSC

12352005

Hazard Statement

H315-H319

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-in-27.html

Purity

98.27

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N#CC(C1C2=CC=C(C)C=C2)=C(N)OC(C3=CC=CC=C3O4)=C1C4=O

Molecular Formula

C20H14N2O3

Molecular Weight

330.34

Precautions

P264-P280-P302+P352-P305+P351+P338-P362+P364

References & Citations

[1]Bouazizi Y, et al. Synthesis of new 3, 4-dihydropyrano [c] chromene derivatives and their evaluation as acetyl cholinesterase inhibitors[J]. European Journal of Chemistry, 2014, 5 (3) : 457-462.