L-NAPNA
L-NAPNA is a nitric oxide synthase (NOS) inhibitor with an IC50 of 1.4 μM. L-NAPNA exhibits analgesic effects by inhibiting formalin-induced paw licking behavior in mice (ED50 of 57.2 mg/kg) and suppressing acetic acid-induced abdominal writhing in mice (ED50 of 25 mg/kg) . L-NAPNA can be used in research related to central nervous system diseases[1].
Product Specifications
CAS Number
85697-89-8
UNSPSC
12352005
Hazard Statement
H302+H312+H332-H315-H319-H335-H350
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/l-napna.html
Smiles
O=C(NC1=CC=C([N+]([O-])=O)C=C1)[C@@H](N)CCCNC(N[N+]([O-])=O)=N
Molecular Formula
C12H17N7O5
Molecular Weight
339.31
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Babbedge RC, et al. L-NG-nitro arginine p-nitroanilide (L-NAPNA) is anti-nociceptive in the mouse. Neuroreport. 1993 Mar;4 (3) :307-10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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