Shishijimicin B
Product Specifications
UNSPSC Description
Shishijimicin B is an active compound of the enediyne class. Shishijimicin B shows extremely potent cytotoxicity with IC50 values of 2.0-3.3 nM. Shishijimicin B has antitumor activity and can be used for the research of cancer[1]. Shishijimicin B is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/shishijimicin-b.html
Solubility
10 mM in DMSO
Smiles
CSSSC/C=C([C@]1(C2)O)\C([C@H](C#C/C=C\C#C1)O[C@H](O[C@@H]3C)[C@@H]([C@H]([C@@H]3C(C4=C(NC5=CC=C6O)C(C5=C6)=CC=N4)=O)O)O[C@H](OC[C@@H]7NC(C)C)C[C@@H]7OC)=C(C2=O)NC(OC)=O
Molecular Weight
935.09
References & Citations
[1]Naoya Oku, et al. Shishijimicins A-C, novel enediyne antitumor antibiotics from the ascidian Didemnum proliferum(1). J Am Chem Soc. 2003 Feb 26;125(8):2044-5.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N10538/Shishijimicin-B-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N10538/
Clinical Information
No Development Reported
CAS Number
503860-51-3
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