Tubulin, alpha (BSA & Azide Free) (Alpha Tubulin, Tubulin alpha Ubiquitous, H2-Alpha, K-alpha-1, TUBA3, Tubulin alpha 1 Chain, TUBA1, TUBA1A, Tubulin K alpha 1) (Biotin)

Recognizes chicken tubulin alpha at ~57kD. Causes the 10nm filaments to collapse into large lateral aggregates collecting in the cell periphery or tight juxtanuclear caps (1). Does not block microtubule assembly (1). Does not inhibit polymerization or depolymerization of platelet tubulin in vitro (3). Blocks (70-80%) the ability of tubulin dimers (with GppNHp bound) to promote a stable inhibition of adenylyl cyclase. Species Crossreactivity: human, bovine, porcine, rat, mouse, guinea pig, gerbil and frog.