Dezecapavir
Dezecapavir (example 4) is a potent inhibitor of HIV replication, with the EC50 of 0.025 nM and CC50 of > 0.5 μM in MT2 cells[1].
Product Specifications
CAS Number
2568911-72-6
Product Name Alternative
VH-499; VH4011499
UNSPSC
12352005
Target
DNA/RNA Synthesis; HIV
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dezecapavir.html
Smiles
FC(F)(CCOC1=NC(N=C(N(C2=O)C3=C(N(N=C4NS(C)(=O)=O)C)C4=C(C=C3)Cl)[C@@H](NC(CN5C6=C(C(C(F)F)=N5)[C@]7([H])[C@@](C(F)6F)([H])C7)=O)CC8=CC(F)=CC(F)=C8)=C2C=C1)F
Molecular Formula
C37H29ClF9N9O5S
Molecular Weight
918.19
References & Citations
[1]ViiV Healthcare UK (No.5) Limited. Inhibitors of human immunodeficiency virus replication. World Intellectual Property Organization, WO2021209900 A1 2021-10-21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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