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SR-4370

SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 μM, 0.58 μM, 0.006 μM, 2.3 μM, and 3.4 μM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively.

Product Specifications

CAS Number

1816294-67-3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/SR-4370.html

Purity

98.38

Solubility

DMSO : ≥ 150 mg/mL

Smiles

O=C(C1=CC=C(C2=CC=CC(F)=C2F)C=C1)NNCCCC

Molecular Formula

C17H18F2N2O

Molecular Weight

304.33

Precautions

H302, H315, H319, H335

References & Citations

[1]LIAO, Daiqing, et al. HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT. WO 2015153516 A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC1; HDAC2; HDAC3; HDAC6; HDAC8

Available Sizes

Frequently Asked Questions

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