SR-4370
SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 μM, 0.58 μM, 0.006 μM, 2.3 μM, and 3.4 μM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively.
Product Specifications
CAS Number
[1816294-67-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SR-4370.html
Purity
98.38
Solubility
DMSO : ≥ 150 mg/mL
Smiles
O=C(C1=CC=C(C2=CC=CC(F)=C2F)C=C1)NNCCCC
Molecular Formula
C17H18F2N2O
Molecular Weight
304.33
Precautions
H302, H315, H319, H335
References & Citations
[1]LIAO, Daiqing, et al. HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT. WO 2015153516 A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC2; HDAC3; HDAC6; HDAC8
Available Sizes
Curated Selection
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