GPR139 agonist-2
GPR139 agonist-2 (compound 20a) is a potent GPR139 agonist with an EC50 of 24.7 nM. GPR139 agonist-2 rescues the social interaction deficits and alleviates cognitive deficits in murine schizophrenia models. GPR139 agonist-2 has the potential for antischizophrenia drug research[1].
Product Specifications
CAS Number
[2983118-29-0]
UNSPSC
12352005
Target
GPR139
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gpr139-agonist-2.html
Purity
99.80
Solubility
DMSO : 25 mg/mL (ultrasonic; warming)
Smiles
O=C1N(CC(N[C@@H](C)C2=CC=C(OC(F)(F)F)C=C2)=O)N=CC3=CC=CN31
Molecular Formula
C17H15F3N4O3
Molecular Weight
380.32
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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