Picoxystrobin

Picoxystrobin is a strobilurin fungicide. Picoxystrobin controls plant diseases by inhibiting mitochondrial respiration. Picoxystrobin is highly toxic to zebrafish embryos, causing developmental abnormalities, oxidative stress, and immunotoxicity[1][2].

Product Specifications

CAS Number

[117428-22-5]

UNSPSC

12352005

Hazard Statement

H332, H410

Target

Fungal; Reactive Oxygen Species (ROS) ; SOD

Type

Reference compound

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/picoxystrobin.html

Concentration

10mM

Purity

99.76

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OC)/C(C(C=CC=C1)=C1COC2=CC=CC(C(F)(F)F)=N2)=C/OC

Molecular Formula

C18H16F3NO4

Molecular Weight

367.32

Precautions

H332, H410

References & Citations

[1]Wei Jia, et al. Effects of two strobilurins (azoxystrobin and picoxystrobin) on embryonic development and enzyme activities in juveniles and adult fish livers of zebrafish (Danio rerio) . Chemosphere. 2018 Sep;207:573-580.|[2]Li H, et al. Developmental toxicity, oxidative stress and immunotoxicity induced by three strobilurins (pyraclostrobin, trifloxystrobin and picoxystrobin) in zebrafish embryos. Chemosphere. 2018 Sep;207:781-790.