Tau (Tau Protein, Microtubule-associated Protein, MAP) (APC)

Recognizes an epitope near the C-terminal region (aa404-441) of human tau. It reacts with all 7 isoforms of human tau (binding-competent and binding-incompetent), A68 (an abnormal phosphorylated derivative of tau), bovine tau and human NeuroFibrillary Tangles (NFTs). Reactivity is independent of the state of tau phosphorylation. Some crossreactivity with MAP2 is also observed.