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Fosfenopril (Standard)

Selected Variant

HY-107352R-01

Size: 1 mg

Fosfenopril (Standard) is the analytical standard of Fosfenopril. This product is intended for research and analytical applications. Fosfenopril (Fosinoprilat) is a potent angiotensin converting enzyme (ACE) inhibitor. Fosfenopril alleviates lipopolysaccharide (LPS) -induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes[1][2].

Product Specifications

CAS Number

95399-71-6

Product Name Alternative

Fosinoprilat (Standard) ; Fosinoprilic acid (Standard) ; SQ 27519 (Standard)

UNSPSC

12352005

Hazard Statement

H360

Target

Angiotensin-converting Enzyme (ACE) ; Interleukin Related; NF-κB; Reference Standards; TNF Receptor; Toll-like Receptor (TLR)

Type

Reference Standards

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/fosfenopril-standard.html

Smiles

O=P(CCCCC1=CC=CC=C1)(O)CC(N2C[C@H](C3CCCCC3)C[C@H]2C(O)=O)=O

Molecular Formula

C23H34NO5P

Molecular Weight

435.49

Precautions

P280-P405-P501

References & Citations

[1]Yang S, et al. Fosinoprilat alleviates lipopolysaccharide (LPS) -induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes. Cell Immunol. 2013 Jul-Aug;284 (1-2) :182-6.|[2]DeForrest JM, et al. Fosinopril, a phosphinic acid inhibitor of angiotensin I converting enzyme: in vitro and preclinical in vivo pharmacology. J Cardiovasc Pharmacol. 1989 Nov;14 (5) :730-6.|[3]DeForrest JM, et al. Blood pressure lowering and renal hemodynamic effects of fosinopril in conscious animal models. J Cardiovasc Pharmacol. 1990 Jul;16 (1) :139-46.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Price

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