Huntingtin Protein, aa1844-2131 (Huntington Disease) (AP)

Reacts with an epitope corresponding to the HDB region (amino acids 1844-2131) of the huntingtin protein. Clone 3H2240 detects a 350kD band on western blots but also detects smaller degradation products of huntingtin. The combined use of clone 3H2240, HDC8A4 and HDA3E10 demonstrate that huntingtin is enriched in neuronal cells in the brain. Species Crossreactivity: human, rabbit, mouse