CD62L (gp90 MEL, hLHRc, L Selectin, L-Selectin, LECAM-1, Lymph Node Homing Receptor, LNHR, Lymphocyte Adhesion Molecule 1, LYAM1, PLNHR, Selectin L, SELL, TQ1) (AP)

Reacts with a 90kD protein involved in the homing of lymphocytes to peripheral lymph nodes (CD62L or L-selectin) L-selectin is expressed on most T and B lymphocytes, neutrophils, monocytes and eosinophils (1). Pre-incubation of lymphocytes with 3H1615 completely and specifically blocks binding of lymphocytes to high endothelial venules (HEV) in vitro and the migration of lymphocytes to lymph nodes in vivo (2). We recommend the azide free product for use in functional studies.