Ac-DMQD-pNA

Ac-DMQD-pNA is a peptide substrate. Both of the recombinant CgCaspase-1 (rCgCaspase-1) and the C-terminus of CgCaspase-1 (rCgCaspase-1-C) exhibits similar caspase activity towards proteolytic substrate Ac-DMQD-pNA and Ac-DEVD-pNA (HY-P1006) [1][2].

Product Specifications

CAS Number

[907589-02-0]

UNSPSC

12352209

Target

Biochemical Assay Reagents

Type

Peptides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ac-dmqd-pna.html

Solubility

H2O

Smiles

O=C(C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NC1=CC=C(C=C1)[N+]([O-])=O)=O)CC(O)=O)=O)CCC(N)=O)=O)CCSC)=O)CC(O)=O

Molecular Formula

C26H35N7O12S

Molecular Weight

669.66

References & Citations

[1]Fang B, et al. Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition. J Mol Biol. 2006 Jul 14;360 (3) :654-66.|[2]Lu G, et al. The self-activation and LPS binding activity of executioner caspase-1 in oyster Crassostrea gigas. Dev Comp Immunol. 2017 Dec;77:330-339.