Integrin alphaV, beta5 (MaxLight 490)
Product Specifications
NCBI Gene ID
3685
Reactivity
Human
Storage Conditions
Store at 4 degree C. Do Not Freeze.
Specificity
Recognizes human integrin alphaVbeta5. Does not recognize integrin alphaVbeta3 or alpha5beta1. Binds to the alphaVbeta5 complex. Has a Kd of 2.8nM in Mn2+, 4.0nM in Ca2+and 2.9nM in buffer lacking cation. Thus, cations do not significantly affect the binding to alphaVbeta5. Does not block ligand binding to purified alphaVbeta5, nor does it block cell adhesion mediated through this receptor.
Other Gene Names
[ITGAV; ITGAV; CD51; MSK8; VNRA; VTNR; MSK8; VNRA]
Short Name
[Integrin alphaV, beta5]
Other Product Names
[integrin alpha-V isoform 2; Integrin alpha-V; integrin alpha-V; integrin alphaVbeta3; vitronectin receptor subunit alpha; antigen identified by monoclonal antibody L230; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); integrin, alpha V; Vitronectin receptor subunit alpha]
NCBI GI Number
223468595
NCBI Accession Number
NP_001138471.1
NCBI GB Accession Number
NM_001144999.2
Uniprot Accession Number
P06756
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