CDK7-IN-31
CDK7-IN-31 (compound 13) is a potent and orally active cyclin-dependent kinase 7 (CDK7) inhibitor with a Kd value of 0.18 nM. CDK7-IN-31 shows anticancer activity[1].
Product Specifications
CAS Number
2943043-62-5
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk7-in-31.html
Smiles
O=C(N(C)CC(CCN1C)(F)F)C2=CC=C3C(C4=NC(N[C@@H]5C[C@@H]1CC5)=NC=C4C(F)(F)F)=CNC3=C2P(C)(C)=O
Molecular Formula
C27H32F5N6O2P
Molecular Weight
598.55
References & Citations
[1]Lu H, et al. Discovery of a Novel Macrocyclic Noncovalent CDK7 Inhibitor for Cancer Therapy. J Med Chem. 2024 Nov 9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK7
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6342172-01 0.2 mL
RIP140, ID (NRIP1, Nuclear receptor-interacting protein 1, Nuclear factor RIP140, Receptor-interacting protein 140) (Biotin)
Sign In for Pricing
View Details MBS6342172-02 5x 0.2 mL
RIP140, ID (NRIP1, Nuclear receptor-interacting protein 1, Nuclear factor RIP140, Receptor-interacting protein 140) (Biotin)
Sign In for Pricing
View Details 
M-5500-03 10 g
4-Methylumbelliferyl-N-acetyl-beta-D-galactosaminide
Sign In for Pricing
View Details M-5500-04 25 g
4-Methylumbelliferyl-N-acetyl-beta-D-galactosaminide
Sign In for Pricing
View Details