CDK7-IN-31
CDK7-IN-31 (compound 13) is a potent and orally active cyclin-dependent kinase 7 (CDK7) inhibitor with a Kd value of 0.18 nM. CDK7-IN-31 shows anticancer activity[1].
Product Specifications
CAS Number
2943043-62-5
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk7-in-31.html
Smiles
O=C(N(C)CC(CCN1C)(F)F)C2=CC=C3C(C4=NC(N[C@@H]5C[C@@H]1CC5)=NC=C4C(F)(F)F)=CNC3=C2P(C)(C)=O
Molecular Formula
C27H32F5N6O2P
Molecular Weight
598.55
References & Citations
[1]Lu H, et al. Discovery of a Novel Macrocyclic Noncovalent CDK7 Inhibitor for Cancer Therapy. J Med Chem. 2024 Nov 9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK7
Frequently Asked Questions
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