Butamben
Butamben (Butyl 4-aminobenzoate) results in long-lasting relief from pain, without impairing motor function or other sensory functions[1][2].
Product Specifications
CAS Number
94-25-7
Product Name Alternative
Butyl 4-aminobenzoate
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Calcium Channel; Potassium Channel; Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Butamben.html
Concentration
10mM
Purity
99.82
Solubility
DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL
Smiles
O=C(OCCCC)C1=CC=C(N)C=C1
Molecular Formula
C11H15NO2
Molecular Weight
193.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Cereda CM, et al. Liposomal butamben gel formulations: toxicity assays and topical anesthesia in an animal model. J Liposome Res. 2017 Mar;27 (1) :74-82.|[2]Rampaart LJA, et, al. The local anesthetic butamben inhibits total and L-type barium currents in PC12 cells. Anesth Analg. 2008 Jun;106 (6) :1778-83.|[3]Kolesnikov YA, et, al. Analgesic synergy between topical morphine and butamben in mice. Anesth Analg. 2003 Oct;97 (4) :1103-7, table of contents.|[4]Berg RJV, et, al. The local anesthetic n-butyl-p-aminobenzoate selectively affects inactivation of fast sodium currents in cultured rat sensory neurons. Anesthesiology. 1995 Jun;82 (6) :1463-73.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
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