Butamben

Butamben (Butyl 4-aminobenzoate) results in long-lasting relief from pain, without impairing motor function or other sensory functions[1][2].

Product Specifications

CAS Number

[94-25-7]

Product Name Alternative

Butyl 4-aminobenzoate

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Calcium Channel; Potassium Channel; Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Butamben.html

Concentration

10mM

Purity

99.82

Solubility

DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL

Smiles

O=C(OCCCC)C1=CC=C(N)C=C1

Molecular Formula

C11H15NO2

Molecular Weight

193.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Cereda CM, et al. Liposomal butamben gel formulations: toxicity assays and topical anesthesia in an animal model. J Liposome Res. 2017 Mar;27 (1) :74-82.|[2]Rampaart LJA, et, al. The local anesthetic butamben inhibits total and L-type barium currents in PC12 cells. Anesth Analg. 2008 Jun;106 (6) :1778-83.|[3]Kolesnikov YA, et, al. Analgesic synergy between topical morphine and butamben in mice. Anesth Analg. 2003 Oct;97 (4) :1103-7, table of contents.|[4]Berg RJV, et, al. The local anesthetic n-butyl-p-aminobenzoate selectively affects inactivation of fast sodium currents in cultured rat sensory neurons. Anesthesiology. 1995 Jun;82 (6) :1463-73.