[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
Product Specifications
UNSPSC Description
[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH acts as a GnRH receptor antagonist[1].
Target Antigen
GnRH Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/d-glp1-d-phe2-d-trp3-6-lh-rh.html
Solubility
10 mM in DMSO
Smiles
OC(C=C1)=CC=C1C[C@H](NC([C@H](CO)NC([C@H](NC([C@H](NC([C@@H]2NC(CC2)=O)=O)CC3=CC=CC=C3)=O)CC4=CNC5=CC=CC=C45)=O)=O)C(N[C@@H](C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N6[C@@H](CCC6)C(NCC(N)=O)=O)=O)=O)=O)CC7=CNC8=CC=CC=C78)=O
Molecular Weight
1321.48
References & Citations
[1]Rivier C, et al. Effect of the LRF-antagonist [D-pGlu1, D-Phe2, D-Trp3,6]-LRF on pregnancy in the rat. Contraception. 1979 Feb;19(2):185-90. |[2]Rivier JE, et al. A potent luteinizing hormone releasing factor antagonist in vitro and inhibitor of ovulation in the rat. Life Sci. 1978 Aug 28;23(8):869-76. |[3]Hsueh AJ, et al. Effect on an antagonistic analog of gonadotropin releasing hormone upon ovarian granulosa cell function. Life Sci. 1979 Oct 1;25(14):1223-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P3671/D-Glp1-D-Phe2-D-Trp3-6-LH-RH-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P3671/
Clinical Information
No Development Reported
CAS Number
68059-94-9
Curated Selection
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