CD117 (c-kit, Stem Cell Factor, SCF Receptor, Steel Factor Receptor, Mast Cell Growth Factor, MGF) (AP)

Product Specifications

Gene Name

[CD117]

NCBI Gene ID

3815

Reactivity

Human

Storage Conditions

Store at 4 degree C. Do Not Freeze.

Specificity

Recognizes c-Kit (CD117, Steel factor receptor and stem cell factor receptor), a transmembrane receptor tyrosine kinase expressed by hematopoietic progenitor cell subsets and mast cells. The interaction of c-Kit and its ligand is required for normal hematopoiesis, mast cell differentiation, melanogenesis and gametogenesis. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia and piebaldism.

Other Gene Names

[KIT; KIT; PBT; SCFR; C-Kit; CD117; SCFR; SCFR; PBT]

Short Name

[CD117]

Other Product Names

[mast/stem cell growth factor receptor Kit isoform 1; Mast/stem cell growth factor receptor Kit; mast/stem cell growth factor receptor Kit; p145 c-kit; proto-oncogene c-Kit; piebald trait protein; soluble KIT variant 1; tyrosine-protein kinase Kit; proto-oncogene tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog]