CD117 (c-kit, Stem Cell Factor, SCF Receptor, Steel Factor Receptor, Mast Cell Growth Factor, MGF) (AP)
Product Specifications
Gene Name
[CD117]
NCBI Gene ID
3815
Reactivity
Human
Storage Conditions
Store at 4 degree C. Do Not Freeze.
Specificity
Recognizes c-Kit (CD117, Steel factor receptor and stem cell factor receptor), a transmembrane receptor tyrosine kinase expressed by hematopoietic progenitor cell subsets and mast cells. The interaction of c-Kit and its ligand is required for normal hematopoiesis, mast cell differentiation, melanogenesis and gametogenesis. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia and piebaldism.
Other Gene Names
[KIT; KIT; PBT; SCFR; C-Kit; CD117; SCFR; SCFR; PBT]
Short Name
[CD117]
Other Product Names
[mast/stem cell growth factor receptor Kit isoform 1; Mast/stem cell growth factor receptor Kit; mast/stem cell growth factor receptor Kit; p145 c-kit; proto-oncogene c-Kit; piebald trait protein; soluble KIT variant 1; tyrosine-protein kinase Kit; proto-oncogene tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog]
NCBI GI Number
4557695
NCBI Accession Number
NP_000213.1
NCBI GB Accession Number
NM_000222.2
Uniprot Accession Number
P10721
Available Sizes
Curated Selection
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