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N- (4-Anilino-1-naphthyl) maleimide

N- (4-Anilino-1-naphthyl) maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N- (4-Anilino-1-naphthyl) maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λex=355 nm, λem=448 nm[1].

Product Specifications

CAS Number

50539-45-2

UNSPSC

12171500

Hazard Statement

H315-H319-H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n-4-anilino-1-naphthyl-maleimide.html

Solubility

10 mM in DMSO

Smiles

O=C(C=C1)N(C2=C3C=CC=CC3=C(NC4=CC=CC=C4)C=C2)C1=O

Molecular Formula

C20H14N2O2

Molecular Weight

314.34

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]T Honda, et al. Characterization of the reactivity of sulphydryl groups in tryptophanase by a dual-monitoring high-performance liquid chromatographic system with a site-directed fluorescent reagent. J Chromatogr. 1986 Dec 26;371:353-60.|[2]S Chaen, et al. Fluorescence properties and contraction characteristics of ANM (N- (1-anilinonaphthyl-4) maleimide) -labeled rabbit psoas muscle fibers. J Biochem. 1985 Oct;98 (4) :939-47.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Frequently Asked Questions

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