Vitamin A-d4
Product Specifications
CAS Number
118063-12-0
UNSPSC Description
Vitamin A-d4 (Vitamin A1-d4; all-trans-Retinol-d4) is the deuterium labeled Vitamin A. Vitamin A is an endogenous metabolite.
Target Antigen
Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
98.0
Solubility
10 mM in DMSO
Smiles
C(=C/C(=C(/C=C/C(=C/CO)/C)\[2H])/C([2H])([2H])[2H])\C=1C(C)(C)CCCC1C
Molecular Weight
290.48
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Zhang M, et al. High-fat diet enhanced retinal dehydrogenase activity, but suppressed retinol dehydrogenase activity in liver of rats. J Pharmacol Sci. 2015 Apr;127(4):430-8.|[3]Miyazaki H, et al. Retinol status and expression of retinol-related proteins in methionine-choline deficient rats. J Nutr Sci Vitaminol (Tokyo). 2014;60(2):78-85.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light, stored under nitrogen
Clinical Information
No Development Reported
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